Professor Simon Lewis is a Consultant Neurologist and Professor of Cognitive Neurology at Macquarie University, internationally recognised for his expertise in Parkinson’s disease and related neurodegenerative disorders. His clinical practice focuses on delivering comprehensive, evidence-based and compassionate care for people living with Parkinson’s disease, Dementia with Lewy Bodies (DLB), Progressive Supranuclear Palsy (PSP), Multiple System Atrophy and isolated REM Sleep Behaviour Disorder (iRBD), a condition increasingly recognised as a prodromal phase of Parkinson’s disease and Lewy body disorders. Through a patient-centred and multidisciplinary approach, he works closely with individuals and families to optimise quality of life, manage complex motor and non-motor symptoms, and provide clear guidance throughout the disease journey. His clinical and research programs integrate advanced neuroimaging, neurophysiology, chronobiology, genetics and biomarker discovery to better understand disease mechanisms and accelerate earlier diagnosis and personalised treatment approaches. His work has also focused on symptoms such as cognitive impairment, hallucinations, gait disturbance, freezing of gait and sleep-wake dysfunction. As Clinical Lead of the Australian Parkinson’s Mission, Professor Lewis plays a central role in one of Australia’s largest collaborative Parkinson’s research initiatives, bringing together clinicians, scientists and patients to develop disease-modifying therapies and innovative biomarker-driven clinical trials. He has published more than 300 peer-reviewed papers and has received major funding support from organisations including the NHMRC, ARC and the Michael J. Fox Foundation. Alongside his clinical work and research leadership, he remains deeply committed to education, advocacy and mentoring the next generation of clinicians and neuroscientists dedicated to improving outcomes for people living with neurodegenerative disease.
